Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 8/20 | 0.69 |
| ▸ | EGFR | P00533 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367826 | 1.00 | PDGFRB (0.71) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL12510337 | 0.89 | PDGFRB (0.58) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL1367379 | 0.85 | PDGFRB (0.58) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL12510338 | 0.80 | PDGFRB (0.55) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL1366483 | 0.79 | PDGFRB (0.57) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL12143409 | 0.78 | PDGFRB (0.55) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL12144353 | 0.78 | KDR (0.61) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL19994265 | 0.71 | KDR (0.43) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL14547909 | 0.71 | MEN1 (0.43) | PDGFRBKDREGFRMEN1KMT2A | |
| SCHEMBL312171 | 0.70 | CHEK1 (0.44) | PDGFRBKDREGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360142-A1 | Multitargeting Agents For The Potential Treatment of Dementia With Lewy Bodies, Parkinson's Disease, and Alzheimer Disease With Lewy Bodies | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | 2024-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360142-A1 | Multitargeting Agents For The Potential Treatment of Dementia With Lewy Bodies, Parkinson's Disease, and Alzheimer Disease With Lewy Bodies | PARK7, SNCA, GRN | PDGFRB 4043/4885KDR 4707/4885EGFR 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.