Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31110251 | 1.00 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25142724 | 1.00 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL31110192 | 1.00 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25142842 | 1.00 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25142415 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25143083 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25142408 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25142399 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL25143000 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL31665214 | 0.90 | RAB9A (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2025-07-24 | — | — | US | disclosed |
| CN-118451078-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, TP53BP1 | RAB9A 3234/4885NPC1 3357/4885ALDH1A1 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.