Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 11/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31110928 | 0.90 | EPAS1 (0.39) | EPAS1BRD4VEGFASLC22A12PGR | |
| SCHEMBL29336696 | 0.84 | EPAS1 (0.38) | EPAS1BRD4VEGFASLC22A12PGR | |
| SCHEMBL29237594 | 0.84 | DRD1 (0.36) | EPAS1BRD4AR | |
| SCHEMBL30967818 | 0.84 | DRD1 (0.36) | EPAS1BRD4AR | |
| SCHEMBL29237576 | 0.82 | TRPA1 (0.34) | EPAS1BRD4VEGFASLC22A12AR | |
| SCHEMBL30967762 | 0.82 | TRPA1 (0.34) | EPAS1BRD4VEGFASLC22A12AR | |
| SCHEMBL31111009 | 0.81 | EPAS1 (0.34) | EPAS1BRD4VEGFASLC22A12 | |
| SCHEMBL31111011 | 0.81 | BRD4 (0.35) | BRD4 | |
| SCHEMBL27270099 | 0.79 | TRPA1 (0.33) | EPAS1BRD4VEGFASLC22A12AR | |
| SCHEMBL31108584 | 0.79 | EPAS1 (0.33) | EPAS1BRD4VEGFAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |