SCHEMBL31111362

SCHEMBL31111362

C[C@](C(=O)N1CCOc2c(C#N)cncc2C1)(C(F)F)C1CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385526 1.00 RIPK1 (1.00) RIPK1
SCHEMBL21867415 1.00 RIPK1 (1.00) RIPK1
SCHEMBL20565165 1.00 RIPK1 (1.00) RIPK1
SCHEMBL21867416 1.00 RIPK1 (1.00) RIPK1
Oditrasertib SCHEMBL20564972 0.87 RIPK1 (0.86) RIPK1
SCHEMBL20564875 0.87 RIPK1 (0.80) RIPK1
SCHEMBL21800542 0.87 RIPK1 (0.78) RIPK1
SCHEMBL20565652 0.85 RIPK1 (0.75) RIPK1
SCHEMBL20565660 0.84 RIPK1 (1.00) RIPK1
SCHEMBL20564546 0.84 RIPK1 (1.00) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110913858-B Kinase inhibitors and uses thereof 戴纳立制药公司 2024-09-24 CN disclosed