SCHEMBL31111385

SCHEMBL31111385

CCCCCCCCCCCCCCCCCCCCCCOc1cc(CO)cc(OCCCCCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRA P10827 3/20 0.45
THRB P10828 3/20 0.45
NR5A1 Q13285 1/20 0.41
MEN1 O00255 1/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADRA2A P08913 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1201515 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1201502 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1201162 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1201128 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1201460 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL4864512 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL96240 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1201657 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL1200630 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2
SCHEMBL29341218 1.00 THRA (0.45) THRATHRBNR5A1MEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
WO-2024182268-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS REGENERON PHARMACEUTICALS, INC. (US) 2024-09-06 WO disclosed