Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31112809 | 1.00 | LMNA (0.47) | LMNAMAPTMAPK1CNR1ALDH1A1 | |
| SCHEMBL31112767 | 1.00 | LMNA (0.47) | LMNAMAPTMAPK1CNR1ALDH1A1 | |
| SCHEMBL31112507 | 0.84 | LMNA (0.51) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL31112534 | 0.84 | LMNA (0.51) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL31112821 | 0.84 | LMNA (0.51) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL31112502 | 0.84 | LMNA (0.51) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL31112781 | 0.84 | LMNA (0.51) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL31606926 | 0.83 | LMNA (0.50) | LMNAMAPTMAPK1CNR1ALDH1A1 | |
| SCHEMBL31606922 | 0.83 | LMNA (0.50) | LMNAMAPTMAPK1CNR1ALDH1A1 | |
| SCHEMBL27952560 | 0.82 | LMNA (0.49) | LMNAMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705289-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | Terran Biosciences Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226691-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. (US) | 2024-10-31 | — | — | WO | disclosed |