Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114121 | 0.85 | KCNH2 (0.46) | KCNH2BRD4PKMRAB9APIK3C3 | |
| SCHEMBL31113619 | 0.83 | IKBKB (0.42) | MAP4K4SYK | |
| SCHEMBL31113637 | 0.80 | KCNH2 (0.48) | KCNH2BRD4PKMRAB9APIK3C3 | |
| SCHEMBL31113732 | 0.80 | KCNH2 (0.53) | KCNH2BRD4RAB9APIK3C3KEAP1 | |
| SCHEMBL31113853 | 0.80 | IKBKB (0.43) | MAP4K4SYK | |
| SCHEMBL31113723 | 0.79 | KCNH2 (0.47) | KCNH2BRD4PKMRAB9AMAP4K4 | |
| Hydrochloric Acid SCHEMBL31114024 | 0.78 | HTR6 (0.47) | KCNH2BRD4PKMRAB9APIK3C3 | |
| Hydrochloric Acid SCHEMBL31114027 | 0.78 | KCNH2 (0.46) | KCNH2BRD4PKMRAB9APIK3C3 | |
| SCHEMBL31113946 | 0.78 | KCNH2 (0.47) | KCNH2PKMMAP4K4HTTSYK | |
| SCHEMBL31114158 | 0.77 | KCNH2 (0.47) | KCNH2PKMMAP4K4LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024186839-A1 | BICYCLIC ARYL SULFONAMIDES, SULFONES, AND SULFONATE ESTERS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |