Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 15/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31113921 | 0.99 | MAP4K4 (0.48) | MAP4K4LRRK2CDK1CDK2MTOR | |
| SCHEMBL31113833 | 0.90 | MAP4K4 (0.44) | MAP4K4LRRK2MTORMKNK1MKNK2 | |
| SCHEMBL31113896 | 0.90 | PDE4A (0.50) | MAP4K4LRRK2CDK1CDK2MTOR | |
| SCHEMBL31113928 | 0.90 | MAP4K4 (0.46) | MAP4K4LRRK2MTORMKNK1MKNK2 | |
| SCHEMBL31114017 | 0.89 | MAP4K4 (0.45) | MAP4K4LRRK2SCN10AMKNK1MKNK2 | |
| SCHEMBL31113885 | 0.84 | LRRK2 (0.43) | MAP4K4LRRK2MTORSMG1 | |
| SCHEMBL31113916 | 0.83 | LRRK2 (0.48) | MAP4K4LRRK2MTOR | |
| SCHEMBL31113900 | 0.81 | PKM (0.46) | MAP4K4MKNK1MKNK2 | |
| SCHEMBL31113906 | 0.80 | PKM (0.46) | MAP4K4MKNK1MKNK2 | |
| SCHEMBL31113899 | 0.80 | PIK3CA (0.56) | MAP4K4LRRK2MTORMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024186839-A1 | BICYCLIC ARYL SULFONAMIDES, SULFONES, AND SULFONATE ESTERS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |