SCHEMBL311173

SCHEMBL311173

Cc1cc([N+](=O)[O-])ccc1Oc1cc(N)cc(Oc2ccc([N+](=O)[O-])cc2C)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 3/20 0.56
CYP3A4 P08684 2/20 0.56
MAPT P10636 6/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
PDE7A Q13946 1/20 0.54
TSHR P16473 2/20 0.50
HTT P42858 3/20 0.47
HSPB1 P04792 2/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4238016 0.88 KMT2A (0.71) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL4233663 0.87 ALDH1A1 (0.65) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL310869 0.84 HTT (0.62) ALDH1A1TDP1MAPTMEN1KMT2A
SCHEMBL9185260 0.84 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL4236476 0.82 ALDH1A1 (0.62) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL1553699 0.81 MAPT (0.57) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL22966227 0.81 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL1192871 0.81 ALDH1A1 (0.58) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL4233241 0.80 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4MAPTMEN1
SCHEMBL4231911 0.80 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed