Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31117825 | 0.95 | NPC1 (0.44) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31117936 | 0.91 | NPC1 (0.43) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31117808 | 0.90 | TP53 (0.43) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31117995 | 0.88 | NPC1 (0.40) | NPC1RAB9AALOX5TP53MAPT | |
| Hydrochloric Acid SCHEMBL31117945 | 0.87 | NPC1 (0.40) | NPC1RAB9AALOX5TP53MAPT | |
| Hydrochloric Acid SCHEMBL31117980 | 0.87 | ALOX5 (0.42) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31117927 | 0.82 | NPC1 (0.39) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31117888 | 0.82 | NPC1 (0.39) | NPC1RAB9AALOX5TP53MAPT | |
| SCHEMBL31118001 | 0.81 | BRD4 (0.44) | CCR2FAAHBCHEACHEMEN1 | |
| SCHEMBL31117818 | 0.81 | BRD4 (0.44) | CCR2FAAHMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680343-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192415-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-19 | — | — | WO | disclosed |