Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 2/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | USP10 | Q14694 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877259 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1PLA2G1BATG4B | |
| SCHEMBL10656466 | 0.84 | KMT2A (0.42) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL11160981 | 0.83 | TDP1 (0.48) | ALDH1A1MAPTTDP1LMNAUSP10 | |
| SCHEMBL31118353 | 0.81 | TDP1 (0.60) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL11114839 | 0.81 | TDP1 (0.45) | ALDH1A1MAPTTDP1PLA2G1BATG4B | |
| SCHEMBL38860 | 0.78 | MEN1 (0.68) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL31118239 | 0.77 | MEN1 (0.55) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL8505688 | 0.77 | KMT2A (0.45) | ALDH1A1MAPTTDP1PLA2G1BATG4B | |
| SCHEMBL10536730 | 0.77 | MEN1 (0.67) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 | |
| SCHEMBL8534878 | 0.77 | MEN1 (0.66) | ALDH1A1MAPTTDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024192147-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2024-09-19 | — | — | WO | disclosed |