Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MPO | P05164 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.59 |
| ▸ | NMBR | P28336 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.55 |
| ▸ | IL1RN | P18510 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167914 | 1.00 | TACR1 (0.77) | TACR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8025702 | 1.00 | TACR1 (0.77) | TACR1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1167913 | 1.00 | TACR1 (0.77) | TACR1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL29401056 | 0.99 | TACR1 (0.75) | TACR1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL29401116 | 0.99 | TACR1 (0.75) | TACR1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL28897384 | 0.99 | TACR1 (0.75) | TACR1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4685036 | 0.99 | TACR1 (0.75) | TACR1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL3950971 | 0.99 | TACR1 (0.75) | TACR1MAPTMEN1KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL27857626 | 0.95 | TACR1 (0.71) | TACR1MAPTMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL8787864 | 0.93 | TACR1 (0.68) | TACR1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666837-A | GPX4 protein degradation agent, preparation method and application thereof | 首都医科大学 | 2024-09-20 | — | — | CN | disclosed |