SCHEMBL31120934

SCHEMBL31120934

Cc1cc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC3(CC2)CC3)nc(N2CC(F)(F)C(F)(F)C2)n1

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31120935 1.00 KIF18A (0.91) KIF18A
SCHEMBL22119413 0.95 KIF18A (1.00) KIF18A
SCHEMBL29371066 0.95 KIF18A (1.00) KIF18A
SCHEMBL22148389 0.95 KIF18A (0.87) KIF18A
SCHEMBL29370637 0.95 KIF18A (0.87) KIF18A
SCHEMBL22148395 0.94 KIF18A (1.00) KIF18A
SCHEMBL29371052 0.94 KIF18A (1.00) KIF18A
SCHEMBL29370844 0.94 KIF18A (1.00) KIF18A
SCHEMBL22148238 0.94 KIF18A (1.00) KIF18A
SCHEMBL22148248 0.94 KIF18A (1.00) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024183710-A1 KIF18A INHIBITING COMPOUND AND USE THEREOF 武汉人福创新药物研发中心有限公司 2024-09-12 — — WO disclosed
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