SCHEMBL31121650

SCHEMBL31121650

C[C@@H](O)[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 11/20 0.40
▸ NPY1R P25929 6/20 0.40
▸ NPY2R P49146 4/20 0.40
▸ NPY5R Q15761 4/20 0.40
▸ GLP1R P43220 8/20 0.40
▸ SCTR P47872 1/20 0.40
▸ C5AR1 P21730 1/20 0.37
▸ GCGR P47871 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1071152 0.92 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5R
SCHEMBL1071150 0.92 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30272461 0.90 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL30645278 0.89 GLP1R (0.47) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL30645268 0.89 C5AR1 (0.42) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL31165493 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL31453810 0.89 NPY4R (0.43) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL30645274 0.89 GLP1R (0.48) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL29948315 0.88 C5AR1 (0.46) NPY4RNPY1RNPY2RNPY5RGLP1R
SCHEMBL31452844 0.88 GLP1R (0.47) GLP1RSCTRGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496381-A Chimeric antigen receptor polypeptide, nucleic acid, vector, lentivirus for simultaneously expressing mbIL-15 cytokine and CXCR5 chemokine receptor and application 天津市第一中心医院 2024-08-16 — — CN disclosed
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