Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123795 | 0.92 | PRMT5 (0.32) | CYP3A4HTTSMN1; SMN2PRMT5WDR77 | |
| SCHEMBL31123743 | 0.92 | PRMT5 (0.32) | CYP3A4HTTSMN1; SMN2PRMT5WDR77 | |
| SCHEMBL31123839 | 0.89 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL21683397 | 0.81 | PRMT5 (0.30) | PRMT5WDR77 | |
| SCHEMBL21685924 | 0.79 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL21683387 | 0.79 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL31123701 | 0.78 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL21684292 | 0.77 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL21061581 | 0.76 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL30004392 | 0.76 | PRMT5 (0.34) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |