Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.35 |
| ▸ | NNMT | P40261 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123701 | 0.94 | PRMT5 (0.36) | PRMT5WDR77NNMT | |
| SCHEMBL22509902 | 0.87 | PRMT5 (0.35) | PRMT5WDR77NNMT | |
| SCHEMBL24659488 | 0.86 | PRMT5 (0.36) | PRMT5WDR77NNMT | |
| SCHEMBL22495013 | 0.85 | PRMT5 (0.37) | PRMT5WDR77NNMT | |
| SCHEMBL31123776 | 0.82 | PRMT5 (0.33) | PRMT5WDR77NNMT | |
| SCHEMBL23535919 | 0.82 | PRMT5 (0.33) | PRMT5WDR77NNMT | |
| SCHEMBL23535968 | 0.82 | PRMT5 (0.33) | PRMT5WDR77NNMT | |
| SCHEMBL31123795 | 0.82 | PRMT5 (0.32) | PRMT5WDR77NNMT | |
| SCHEMBL31123743 | 0.82 | PRMT5 (0.32) | PRMT5WDR77NNMT | |
| SCHEMBL24595461 | 0.82 | PRMT5 (0.37) | PRMT5WDR77NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |