Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123788 | 0.86 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL31123769 | 0.83 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL31123792 | 0.78 | PRMT5 (0.62) | PRMT5WDR77 | |
| SCHEMBL23535874 | 0.77 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL31123838 | 0.77 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL20733594 | 0.73 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL20721553 | 0.73 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL21683022 | 0.73 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL21683024 | 0.73 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL30004448 | 0.73 | PRMT5 (0.41) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |