Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 15/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.49 |
| ▸ | TSHR | P16473 | 13/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | USP2 | O75604 | 7/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682074 | 1.00 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30908317 | 0.86 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30908321 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL21551236 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL31091853 | 0.78 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL21682003 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30380040 | 0.77 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL24493061 | 0.77 | MAPT (0.52) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL30578194 | 0.77 | MAPT (0.52) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL27143212 | 0.76 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |