Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124464 | 0.92 | HTT (0.48) | HTTTDP1NPSR1GAAMEN1 | |
| SCHEMBL4666845 | 0.79 | HTT (0.46) | HTTTDP1NPSR1ALDH1A1GFER | |
| SCHEMBL31124495 | 0.79 | CA1 (0.42) | HTTTDP1NPSR1ALDH1A1GFER | |
| SCHEMBL31124393 | 0.74 | ATR (0.37) | HTTGAAMEN1KMT2ACTSS | |
| SCHEMBL8293454 | 0.74 | NQO2 (0.51) | HTTTDP1NPSR1ALDH1A1GFER | |
| SCHEMBL31124399 | 0.72 | TDP1 (0.50) | HTTTDP1GAAMEN1KMT2A | |
| SCHEMBL23979680 | 0.72 | HTT (0.51) | HTTTDP1NPSR1ALDH1A1GFER | |
| SCHEMBL22452382 | 0.72 | TDP1 (0.45) | HTTTDP1NPSR1ALDH1A1GFER | |
| SCHEMBL31124334 | 0.71 | TDP1 (0.46) | HTTTDP1GAAMEN1KMT2A | |
| SCHEMBL31124359 | 0.70 | TDP1 (0.44) | HTTTDP1NPSR1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |