Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124464 | 0.79 | HTT (0.48) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL31124334 | 0.78 | TDP1 (0.46) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL31124333 | 0.76 | TDP1 (0.43) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL30660385 | 0.71 | CA1 (0.44) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL11929438 | 0.71 | TDP1 (0.51) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL31124368 | 0.70 | HTT (0.50) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL3020258 | 0.70 | TDP1 (0.81) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL569251 | 0.70 | TDP1 (0.74) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL4666845 | 0.70 | HTT (0.46) | TDP1GAAMEN1KMT2AMAOA | |
| SCHEMBL31124495 | 0.69 | CA1 (0.42) | TDP1GAAMEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |