SCHEMBL31124657

SCHEMBL31124657

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.57
▸ OPRD1 P41143 4/20 0.55
▸ OPRM1 P35372 2/20 0.55
▸ NMUR2 Q9GZQ4 5/20 0.55
▸ NMUR1 Q9HB89 5/20 0.55
▸ NTSR1 P30989 1/20 0.53
▸ RAMP3 O60896 4/20 0.53
▸ CALCR P30988 4/20 0.53
▸ C5AR1 P21730 1/20 0.52
▸ MAPK8 P45983 1/20 0.52
▸ MAPK9 P45984 1/20 0.52
▸ MAPK10 P53779 1/20 0.52
▸ APLNR P35414 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31129136 0.93 OPRD1 (0.56) EPHA2OPRD1NMUR2NMUR1NTSR1
SCHEMBL31129142 0.91 OPRD1 (0.57) OPRD1NMUR2NMUR1NTSR1RAMP3
SCHEMBL29842931 0.90 EPHA2 (0.54) EPHA2OPRD1OPRM1NMUR2NMUR1
SCHEMBL31129141 0.89 C5AR1 (0.59) EPHA2OPRD1OPRM1NTSR1C5AR1
SCHEMBL31129138 0.89 OPRD1 (0.61) EPHA2OPRD1OPRM1NTSR1C5AR1
SCHEMBL30974482 0.89 NMUR2 (0.60) EPHA2OPRD1OPRM1NMUR2NMUR1
SCHEMBL31129133 0.89 OPRD1 (0.62) EPHA2OPRD1OPRM1NTSR1C5AR1
SCHEMBL30974500 0.89 MAPK8 (0.60) NMUR2NMUR1RAMP3CALCRMAPK8
SCHEMBL31511426 0.88 MAPK8 (0.57) EPHA2OPRD1NMUR2NMUR1NTSR1
SCHEMBL31191279 0.87 MAPK8 (0.58) OPRD1OPRM1NMUR2NMUR1RAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119139448-B Lumbricus peptide and medical application thereof 山东中医药大学 2025-05-16 — — CN disclosed
CN-119139448-A Lumbricus peptide and medical application thereof 山东中医药大学 2024-12-17 — — CN disclosed
CN-118684736-B Lumbricus peptide and its preparation method and use for relieving cough and asthma 山东中医药大学 2024-10-29 — — CN disclosed
CN-118684736-A Lumbricus peptide and its preparation method and use for relieving cough and asthma 山东中医药大学 2024-09-24 — — CN disclosed
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