Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31124702

O=C(O)C(F)(F)F.O=C(O)CCN1CC[C@@H](F)C1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.40
DPP4 P27487 12/20 0.36
DPP7 Q9UHL4 11/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM1A O60341 1/20 0.35
DPP9 Q86TI2 1/20 0.34
DPP8 Q6V1X1 2/20 0.34
SFRP1 Q8N474 1/20 0.34
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31124700 0.94 CYP1A2 (0.39) GLADPP4DPP7ALDH1A1LMNA
SCHEMBL31124637 0.91 GLA (0.46) GLAALDH1A1LMNAGAAKMT2A
SCHEMBL31124629 0.84 SMN1; SMN2 (0.44) GLADPP4DPP7ALDH1A1LMNA
SCHEMBL31448157 0.81 CYP1A2 (0.53) LMNAKMT2AKDM1ACYP1A2MAPK1
SCHEMBL1007110 0.75 L3MBTL1 (0.52) DPP4DPP7ALDH1A1LMNAGAA
SCHEMBL1007601 0.75 L3MBTL1 (0.52) DPP4DPP7ALDH1A1LMNAGAA
Trifluoroacetic Acid SCHEMBL14737009 0.73 DPP7 (0.47) DPP4DPP7DPP9DPP8
Trifluoroacetic Acid SCHEMBL29505594 0.73 DPP7 (0.43) DPP4DPP7DPP9DPP8
Trifluoroacetic Acid SCHEMBL29505595 0.72 SMN1; SMN2 (0.41) DPP4DPP7DPP9DPP8SMN1; SMN2
SCHEMBL9488186 0.72 POLB (0.50) GLAALDH1A1LMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024204554-A1 SPIROCYCLIC MORPHINAN DERIVATIVE 日本ケミファ株式会社 2024-10-03 WO disclosed