Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199789 | 0.88 | ADORA2A (0.44) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL2198592 | 0.88 | TLR7 (0.41) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL4553782 | 0.88 | ADORA2A (0.44) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL29809145 | 0.88 | TLR7 (0.48) | ADORA2AADORA2BTLR7 | |
| SCHEMBL567681 | 0.88 | TLR7 (0.48) | ADORA2AADORA2BTLR7 | |
| SCHEMBL2197624 | 0.87 | TLR7 (0.38) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL2195612 | 0.87 | ADORA2A (0.42) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL2198248 | 0.86 | ADORA2A (0.35) | ADORA2AADORA2BADORA3ADORA1TLR7 | |
| SCHEMBL31124759 | 0.85 | ADORA2A (0.40) | ADORA2AADORA2BADORA3TLR7 | |
| SCHEMBL12157657 | 0.85 | PDE8B (0.38) | ADORA2AADORA2BADORA3ADORA1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024199063-A1 | PHOSPHORUS OR SULFUR-CONTAINING MACROCYCLE AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118724963-A | Macrocyclic compounds containing phosphorus or sulfur and use thereof | 浙江养生堂天然药物研究所有限公司 | 2024-10-01 | — | — | CN | disclosed |