Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 6/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | SERPINA3 | P01011 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126557 | 0.87 | PNP (0.38) | PNPTLR7YTHDC1PDE4APDE4B | |
| SCHEMBL31124774 | 0.87 | TLR7 (0.37) | TLR7 | |
| SCHEMBL31126606 | 0.81 | PNP (0.43) | PNPTLR7YTHDC1PDE4APDE4B | |
| SCHEMBL31126549 | 0.80 | TLR7 (0.40) | PNPTLR7YTHDC1PDE4APDE4B | |
| SCHEMBL31126561 | 0.79 | PNP (0.38) | PNPTLR7YTHDC1PDE4APDE4B | |
| SCHEMBL31126531 | 0.77 | TLR7 (0.49) | PNPTLR7YTHDC1PDE4APDE4B | |
| SCHEMBL31124745 | 0.77 | TLR7 (0.40) | TLR7 | |
| SCHEMBL31126588 | 0.75 | TLR7 (0.37) | TLR7 | |
| SCHEMBL31126597 | 0.74 | TLR7 (0.37) | TLR7ADORA2AADORA1 | |
| SCHEMBL3931613 | 0.69 | TLR7 (0.49) | PNPTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724963-A | Macrocyclic compounds containing phosphorus or sulfur and use thereof | 浙江养生堂天然药物研究所有限公司 | 2024-10-01 | — | — | CN | disclosed |