SCHEMBL31126549 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TLR7	Q9NYK1	2/20	0.40

▸	PNP	P00491	6/20	0.39

▸	PDE4A	P27815	1/20	0.39

▸	PDE4B	Q07343	1/20	0.39

▸	PDE4C	Q08493	1/20	0.39

▸	PDE4D	Q08499	1/20	0.39

▸	YTHDC1	Q96MU7	5/20	0.38

▸	ADORA2A	P29274	2/20	0.37

▸	ADORA1	P30542	1/20	0.37

▸	SERPINA3	P01011	1/20	0.35

▸	PI4KA	P42356	1/20	0.34

▸	PI4K2B	Q8TCG2	1/20	0.34

▸	PI4K2A	Q9BTU6	1/20	0.34

▸	PI4KB	Q9UBF8	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31126557	0.90	PNP (0.38)	TLR7PNPPDE4APDE4BPDE4C
SCHEMBL31126537	0.87	TLR7 (0.39)	TLR7
SCHEMBL31126574	0.87	TLR7 (0.39)	TLR7ADORA2AADORA1
SCHEMBL31126561	0.84	PNP (0.38)	TLR7PNPPDE4APDE4BPDE4C
SCHEMBL31126606	0.81	PNP (0.43)	TLR7PNPPDE4APDE4BPDE4C
SCHEMBL31124753	0.80	PNP (0.38)	TLR7PNPPDE4APDE4BPDE4C
SCHEMBL31126591	0.79	YTHDC1 (0.45)	PDE4APDE4BPDE4CPDE4DYTHDC1
SCHEMBL31126531	0.78	TLR7 (0.49)	TLR7PNPPDE4APDE4BPDE4C
SCHEMBL31126588	0.77	TLR7 (0.37)	TLR7
SCHEMBL31126597	0.77	TLR7 (0.37)	TLR7ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024199063-A1	PHOSPHORUS OR SULFUR-CONTAINING MACROCYCLE AND USE THEREOF	浙江养生堂天然药物研究所有限公司	2024-10-03	—	—	WO	disclosed