Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 9/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966825 | 0.73 | PTPN11 (0.43) | SCN10ACHRNB2CHRNA2CHRNB4CHRNA3 | |
| SCHEMBL28723850 | 0.70 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL30966843 | 0.70 | CHRNB2 (0.38) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16164683 | 0.67 | KCNQ3 (0.41) | ABL1 | |
| SCHEMBL4253983 | 0.67 | EGLN1 (0.36) | EGLN1OGAPGK1 | |
| SCHEMBL28941027 | 0.65 | KDM4E (0.40) | — | |
| SCHEMBL31513363 | 0.65 | EGFR (0.38) | — | |
| SCHEMBL15730262 | 0.63 | CYP1A2 (0.47) | OGACHRNB2CHRNA2CHRNB4CHRNA3 | |
| SCHEMBL19814239 | 0.63 | GAA (0.49) | ABL1 | |
| SCHEMBL15923164 | 0.63 | FFAR1 (0.35) | EGLN1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |