Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26517562 | 0.81 | PAX8 (0.48) | PAX8GRIN2BKDM1ABRD4NPY5R | |
| SCHEMBL23932441 | 0.81 | PAX8 (0.48) | PAX8GRIN2BKDM1ABRD4NPY5R | |
| SCHEMBL30683332 | 0.77 | KDM1A (0.51) | KDM1ANPY5R | |
| SCHEMBL9320214 | 0.76 | NPY5R (0.58) | KDM1ANPY5R | |
| SCHEMBL31127011 | 0.75 | SLC6A2 (0.49) | PAX8GRIN2BKDM1A | |
| SCHEMBL14704615 | 0.73 | GRIN2B (0.67) | GRIN2B | |
| SCHEMBL22055793 | 0.73 | CYP2C9 (0.54) | PAX8NPY5R | |
| SCHEMBL30514948 | 0.72 | BRD4 (0.46) | GRIN2BBRD4 | |
| SCHEMBL26910596 | 0.71 | PAX8 (0.42) | PAX8KDM1ABRD4 | |
| SCHEMBL26099344 | 0.71 | PAX8 (0.42) | PAX8KDM1ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660879-A | Bicyclic indole glucocorticoid receptor antagonists | 科赛普特治疗公司 | 2024-09-17 | — | — | CN | disclosed |