SCHEMBL31127701

SCHEMBL31127701

O=C(Oc1c[nH]nn1)N1CCCCC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 5/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 3/20 0.44
HTT P42858 2/20 0.44
NPC1 O15118 3/20 0.43
LMNA P02545 2/20 0.43
RAB9A P51151 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 3/20 0.43
GAA P10253 1/20 0.42
TSHR P16473 3/20 0.42
HSD17B10 Q99714 1/20 0.42
LIPA P38571 3/20 0.41
BCHE P06276 1/20 0.39
LIPE Q05469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31693566 0.98 ALDH1A1 (0.49) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL31662979 0.73 ALDH1A1 (0.56) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL31662981 0.73 ALDH1A1 (0.56) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL7559945 0.72
SCHEMBL9428936 0.70 SMN1; SMN2 (0.45) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL28570056 0.70 KMT2A (0.44) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL29026363 0.70 SMN1; SMN2 (0.49) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL30311143 0.70 ALDH1A1 (0.47) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL5431818 0.69 GNE (0.44) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL31605051 0.69 ALDH1A1 (0.50) ALDH1A1POLBSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688741-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES Meta-Immune, Inc. (KR) 2026-02-11 EP disclosed
WO-2025081045-A9 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-12-26 WO disclosed
EP-4661875-A1 COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE Celgene Corporation (US) 2025-12-17 EP disclosed
WO-2024249867-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES AM SCIENCES (KR) 2024-12-05 WO disclosed
WO-2024167950-A1 COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE CELGENE CORPORATION (US) 2024-08-15 WO disclosed