Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 3/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128241 | 1.00 | PDE10A (0.35) | PDE10APDE1BCHRM3PDE4APDE4B | |
| SCHEMBL31128304 | 0.82 | SMPD3 (0.39) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL31128206 | 0.82 | SMPD3 (0.39) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL31128194 | 0.80 | SMPD3 (0.39) | PDE10ASMPD3 | |
| SCHEMBL31128322 | 0.80 | SMPD3 (0.39) | PDE10ASMPD3 | |
| SCHEMBL31128254 | 0.74 | CHRM4 (0.37) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31128276 | 0.74 | NCF1 (0.38) | — | |
| SCHEMBL7949976 | 0.72 | CARM1 (0.37) | PDE1BUSP30NTSR1 | |
| SCHEMBL31128391 | 0.70 | MAPK1 (0.47) | PIK3CA | |
| SCHEMBL24824099 | 0.69 | TYK2 (0.35) | PDE1BUSP30TYK2FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024166131-A1 | HETEROARYL COMPOUNDS AS PKMYT1 INHIBITORS | SATYARX PHARMA INNOVATIONS PRIVATE LIMITED (IN) | 2024-08-15 | — | — | WO | disclosed |