Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727148 | 0.82 | HPGD (0.51) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL29697321 | 0.82 | HPGD (0.51) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL25218344 | 0.79 | ALDH1A1 (0.43) | NOTUMCYP19A1AAK1 | |
| SCHEMBL31277054 | 0.79 | ALDH1A1 (0.43) | NOTUMCYP19A1AAK1 | |
| SCHEMBL1260021 | 0.74 | NOTUM (0.55) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL20536197 | 0.73 | CYP19A1 (0.52) | NOTUMCYP19A1AAK1 | |
| SCHEMBL30412461 | 0.73 | NOTUM (0.72) | NOTUMKEAP1 | |
| SCHEMBL2627225 | 0.73 | NOTUM (0.59) | NOTUMKEAP1 | |
| SCHEMBL20766489 | 0.71 | NOTUM (0.41) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL31717453 | 0.71 | TSHR (0.49) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024158872-A1 | 1,3-INDOLE-PROPANAMIDE INHIBITORS OF SARS-COV-2 PLPRO/NSP3 AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-08-02 | — | — | WO | disclosed |