Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31130360 | 0.91 | NPC1 (0.46) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL31130529 | 0.90 | MAPK1 (0.48) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8368151 | 0.86 | MAPT (0.58) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL31130219 | 0.85 | MAPT (0.60) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL31130373 | 0.85 | NPC1 (0.49) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL29819664 | 0.85 | MAPT (0.60) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL1221564 | 0.79 | MEN1 (0.61) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8589802 | 0.78 | KMT2A (0.59) | MAPK1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL3450312 | 0.78 | POLB (0.56) | MAPK1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL3448539 | 0.77 | MAPT (0.55) | MAPK1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4442318-A2 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2024-10-09 | — | — | EP | disclosed |