Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALPL | P05186 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31130185 | 0.86 | MAPK1 (0.54) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL1413939 | 0.86 | MAPT (0.59) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL3450312 | 0.86 | POLB (0.56) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL8366709 | 0.85 | RAB9A (0.57) | MAPTNPC1RAB9AMAPK1ALPL | |
| SCHEMBL3448539 | 0.85 | MAPT (0.55) | MAPTNPC1RAB9AMAPK1ALPL | |
| SCHEMBL8369776 | 0.85 | NPC1 (0.57) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL4557695 | 0.85 | DYRK1A (0.60) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL1221564 | 0.84 | MEN1 (0.61) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL31130219 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9AMAPK1LMNA | |
| SCHEMBL29819664 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |