Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.48 |
| ▸ | HRH1 | P35367 | 6/20 | 0.48 |
| ▸ | HRH2 | P25021 | 5/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25934061 | 1.00 | HRH3 (0.48) | HRH3HRH1HRH2SLC2A1HTR1A | |
| SCHEMBL25933991 | 0.87 | HRH3 (0.52) | HRH3HRH1HRH2SLC2A1HTR1A | |
| SCHEMBL31131417 | 0.87 | HRH3 (0.52) | HRH3HRH1HRH2SLC2A1HTR1A | |
| SCHEMBL25933930 | 0.86 | HRH3 (0.51) | HRH3HRH1HRH2SLC2A1HTR1A | |
| SCHEMBL25438108 | 0.86 | HRH3 (0.44) | HRH3HRH1HRH2HTR1ADRD2 | |
| SCHEMBL30493223 | 0.82 | HRH2 (0.43) | HRH3HRH1HRH2 | |
| SCHEMBL25329631 | 0.81 | AR (0.43) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL25330105 | 0.75 | AR (0.39) | — | |
| SCHEMBL25330053 | 0.75 | AR (0.44) | HRH3HRH1HRH2 | |
| SCHEMBL25933903 | 0.74 | HRH3 (0.66) | HRH3HRH1HRH2SLC2A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574821-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-08-30 | — | — | CN | disclosed |