Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.51 |
| ▸ | HRH1 | P35367 | 7/20 | 0.51 |
| ▸ | HRH2 | P25021 | 6/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31131417 | 0.90 | HRH3 (0.52) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL25933991 | 0.90 | HRH3 (0.52) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL31131390 | 0.86 | HRH3 (0.48) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL25934061 | 0.86 | HRH3 (0.48) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL25329631 | 0.82 | AR (0.43) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL30493265 | 0.82 | HRH2 (0.45) | HRH3HRH1HRH2KCNH2CYP3A4 | |
| SCHEMBL25330438 | 0.82 | HRH2 (0.45) | HRH3HRH1HRH2KCNH2CYP3A4 | |
| SCHEMBL25933903 | 0.76 | HRH3 (0.66) | HRH3HRH1HRH2SLC2A1KCNH2 | |
| SCHEMBL25330053 | 0.75 | AR (0.44) | HRH3HRH1HRH2 | |
| SCHEMBL25329713 | 0.75 | HRH3 (0.40) | HRH3HRH1HRH2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |