Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24569368 | 0.80 | NR1H2 (0.36) | NR1H2CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL24569422 | 0.80 | NR1H2 (0.36) | NR1H2CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL24570200 | 0.77 | NAMPT (0.34) | NR1H2CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL23608642 | 0.71 | DDB1 (0.33) | NR1H2RORCDDB1CRBNKDM1A | |
| SCHEMBL28850072 | 0.71 | DDB1 (0.33) | NR1H2RORCDDB1CRBNKDM1A | |
| SCHEMBL26663115 | 0.71 | CHRM2 (0.38) | NR1H2RORCCHRM2CHRM1CHRM3 | |
| SCHEMBL30489214 | 0.70 | CHRM2 (0.34) | NR1H2RORCCHRM2CHRM1CHRM3 | |
| SCHEMBL25650062 | 0.70 | CHRM2 (0.34) | NR1H2RORCCHRM2CHRM1CHRM3 | |
| SCHEMBL23580148 | 0.70 | NR1H2 (0.41) | NR1H2RORCLIPEDDB1CRBN | |
| SCHEMBL20400032 | 0.68 | DDB1 (0.41) | NR1H2RORCLIPEDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688156-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201322-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | WO | disclosed |