Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 3/20 | 0.46 |
| ▸ | DGKZ | Q13574 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527307 | 1.00 | DGKA (0.46) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL23527176 | 0.94 | DGKA (0.52) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL31133750 | 0.94 | DGKA (0.52) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL31133736 | 0.94 | DGKA (0.46) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL23527004 | 0.94 | DGKA (0.46) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL31133498 | 0.94 | HRH3 (0.47) | DGKADGKZFPR2PROKR1HRH3 | |
| SCHEMBL23527095 | 0.94 | HRH3 (0.47) | DGKADGKZFPR2PROKR1HRH3 | |
| SCHEMBL23527042 | 0.93 | DGKA (0.45) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL31133628 | 0.93 | DGKA (0.45) | DGKADGKZCHRM4FPR2PROKR1 | |
| SCHEMBL23526862 | 0.93 | DGKA (0.47) | DGKADGKZCHRM4SCDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |