Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.44 |
| ▸ | DGKZ | Q13574 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527014 | 1.00 | DGKA (0.44) | DGKADGKZFPR2PROKR1MCHR1 | |
| SCHEMBL31133615 | 0.92 | CHRM4 (0.47) | DGKADGKZCHRM4SCDHRH1 | |
| SCHEMBL31133600 | 0.92 | DGKA (0.41) | DGKADGKZMCHR1CHRM4SCD | |
| SCHEMBL31133671 | 0.92 | DGKA (0.41) | DGKADGKZFPR2PROKR1MCHR1 | |
| SCHEMBL23527156 | 0.92 | DGKA (0.41) | DGKADGKZFPR2PROKR1MCHR1 | |
| SCHEMBL23527041 | 0.92 | DGKA (0.41) | DGKADGKZMCHR1CHRM4SCD | |
| SCHEMBL23527221 | 0.92 | CHRM4 (0.47) | DGKADGKZCHRM4SCDHRH1 | |
| SCHEMBL23527107 | 0.91 | GPR6 (0.43) | DGKADGKZMCHR1CHRM4SCN9A | |
| SCHEMBL31133689 | 0.91 | GPR6 (0.43) | DGKADGKZMCHR1CHRM4SCN9A | |
| SCHEMBL23526862 | 0.91 | DGKA (0.47) | DGKADGKZMCHR1CHRM4SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |