Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20608936 | 0.94 | MAPT (0.54) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL21816823 | 0.82 | MAPT (0.48) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL21816812 | 0.80 | MAPT (0.61) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL10915347 | 0.80 | MAPT (0.61) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL9976072 | 0.80 | MEN1 (0.66) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL23698749 | 0.79 | MAPT (0.46) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL21816877 | 0.79 | MAPT (0.54) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL21816800 | 0.79 | MAPT (0.60) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL21816865 | 0.78 | MAPT (0.58) | MAPTALDH1A1KMT2ACTSBKDM4E | |
| SCHEMBL6974167 | 0.77 | JMJD7 (0.63) | MAPTALDH1A1KMT2ACTSBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401964-B | Compound with BRD4 inhibitory activity, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-10-01 | — | — | CN | disclosed |