SCHEMBL31134166

SCHEMBL31134166

CCOC(=O)/C=C(/C)CC(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.48
HCAR2 Q8TDS4 1/20 0.41
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35
CCR6 P51684 1/20 0.35
BLM P54132 1/20 0.35
MCL1 Q07820 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35
GLO1 Q04760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15482412 1.00 NPSR1 (0.48) NPSR1HCAR2ALDH1A1TDP1LMNA
SCHEMBL15482431 0.85 HCAR2 (0.44) NPSR1HCAR2ALDH1A1TDP1TSHR
SCHEMBL15482562 0.82 NPSR1 (0.47) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL15482432 0.81 TDP1 (0.41) ALDH1A1TDP1LMNAHSD17B10KDM4E
SCHEMBL15482576 0.79 TDP1 (0.42) ALDH1A1TDP1MAPTTSHRCYP2C9
SCHEMBL20878796 0.79 ALDH1A1 (0.42) HCAR2ALDH1A1TDP1TSHRPRKCA
SCHEMBL15482551 0.79 ALDH1A1 (0.42) HCAR2ALDH1A1TDP1TSHRPRKCA
SCHEMBL9512735 0.79 NPSR1 (0.56) NPSR1HCAR2ALDH1A1TDP1LMNA
SCHEMBL2952591 0.79 NPSR1 (0.56) NPSR1HCAR2ALDH1A1TDP1LMNA
SCHEMBL2948325 0.79 NPSR1 (0.56) NPSR1HCAR2ALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496114-A Preparation method of pregabalin 威海海洋职业学院 2024-08-16 CN disclosed