Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PRF1 | P14222 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13554892 | 0.82 | KCNJ1 (0.60) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL1702314 | 0.82 | PRF1 (0.65) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL29861325 | 0.82 | PRF1 (0.65) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL13870507 | 0.82 | KCNJ1 (0.60) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL8276532 | 0.81 | MAOA (0.62) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL2724252 | 0.81 | KCNJ1 (0.59) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL2722639 | 0.79 | KCNJ1 (0.66) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL286654 | 0.79 | KCNJ1 (0.66) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL19367891 | 0.79 | KCNJ1 (0.66) | KCNJ1KCNH2MAPTLMNAGAA | |
| SCHEMBL1656137 | 0.79 | MAOA (0.60) | KCNJ1KCNH2MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222614-A1 | HETEROCYCLIC GSPT1 DEGRADATION AGENT | 北京诺诚健华医药科技有限公司 | 2024-10-31 | — | — | WO | disclosed |