Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478144 | 0.84 | PARG (0.46) | KDM4ETSHRADORA2BALDH1A1 | |
| SCHEMBL25422664 | 0.84 | PARG (0.46) | KDM4ETSHRADORA2BALDH1A1 | |
| SCHEMBL25439300 | 0.82 | PARG (0.46) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL25424268 | 0.80 | PARG (0.47) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL25725101 | 0.80 | MAPT (0.49) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL25422095 | 0.79 | PARG (0.48) | KMT2AMEN1ALDH1A1LMNACYP2D6 | |
| SCHEMBL31135590 | 0.78 | PARG (0.43) | KDM4ETSHRMAPTALDH1A1 | |
| SCHEMBL22716908 | 0.78 | MPO (0.46) | KDM4EKMT2AMAPTMPOALDH1A1 | |
| SCHEMBL31189225 | 0.78 | MPO (0.46) | KDM4EKMT2AMAPTMPOALDH1A1 | |
| SCHEMBL25724418 | 0.78 | PARG (0.46) | KDM4ETSHRKMT2AMEN1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | claimed |
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | disclosed |