SCHEMBL31138564

SCHEMBL31138564

COc1ncnc(C2CC2)c1-c1nc(OCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2c(ccn2CS(C)(=O)=O)n1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.60
▸ WDR48 Q8TAF3 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31138736 0.94 USP1 (0.60) USP1WDR48
SCHEMBL31138535 0.90 USP1 (0.63) USP1WDR48
SCHEMBL31138693 0.90 USP1 (0.59) USP1WDR48
SCHEMBL31138503 0.90 USP1 (0.62) USP1WDR48
SCHEMBL31138731 0.90 USP1 (0.63) USP1WDR48
SCHEMBL31138384 0.89 USP1 (0.62) USP1WDR48
SCHEMBL31138430 0.89 USP1 (0.61) USP1WDR48
SCHEMBL31138393 0.89 USP1 (0.61) USP1WDR48
SCHEMBL31138713 0.87 USP1 (0.59) USP1WDR48
SCHEMBL31138423 0.86 USP1 (0.59) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233605-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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