Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 12/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498619 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2PDE2APDE10AHSD11B1 | |
| SCHEMBL31141506 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2PDE2APDE10AHSD11B1 | |
| SCHEMBL19876978 | 0.89 | CYP11B1 (0.39) | CYP11B1CYP11B2PDE2APDE10AHSD11B1 | |
| SCHEMBL18498642 | 0.83 | CYP11B1 (0.35) | CYP11B1CYP11B2NPSR1 | |
| SCHEMBL31141510 | 0.82 | CYP11B1 (0.35) | CYP11B1CYP11B2PTGS2 | |
| SCHEMBL18506217 | 0.82 | CYP11B1 (0.35) | CYP11B1CYP11B2PTGS2 | |
| SCHEMBL31141489 | 0.81 | NOTUM (0.40) | PDE2APDE10ACYP2C9 | |
| SCHEMBL18498690 | 0.81 | NOTUM (0.40) | PDE2APDE10ACYP2C9 | |
| SCHEMBL17941449 | 0.79 | MEN1 (0.37) | CYP11B1CYP11B2PDE2ANT5ECYP2C9 | |
| SCHEMBL29679685 | 0.79 | MEN1 (0.37) | CYP11B1CYP11B2PDE2ANT5ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955472-A | 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides | 拜耳作物科学股份公司 | 2024-11-15 | — | — | CN | disclosed |