Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498690 | 1.00 | NOTUM (0.40) | NOTUMMAPTCYP2C9KDM4EALDH1A1 | |
| SCHEMBL19877212 | 0.89 | MAPT (0.37) | NOTUMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL18506249 | 0.84 | DDR1 (0.35) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18498705 | 0.84 | POLB (0.33) | NOTUMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL18498637 | 0.83 | POLB (0.46) | NOTUMMAPTALDH1A1HPGDAGPAT2 | |
| SCHEMBL31141521 | 0.83 | POLB (0.46) | NOTUMMAPTALDH1A1HPGDAGPAT2 | |
| SCHEMBL31141506 | 0.81 | CYP11B1 (0.39) | CYP2C9PDE2APDE10A | |
| SCHEMBL31141505 | 0.81 | CYP11B1 (0.39) | CYP2C9PDE2APDE10A | |
| SCHEMBL18498619 | 0.81 | CYP11B1 (0.39) | CYP2C9PDE2APDE10A | |
| SCHEMBL21796215 | 0.81 | MAPT (0.32) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955472-A | 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides | 拜耳作物科学股份公司 | 2024-11-15 | — | — | CN | disclosed |