SCHEMBL31141900

SCHEMBL31141900

O=[N+]([O-])c1ccc2ncc(Br)n2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 7/20 0.48
ALDH1A1 P00352 4/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 1/20 0.48
LMNA P02545 4/20 0.43
GAA P10253 2/20 0.43
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
POLB P06746 2/20 0.39
STAT3 P40763 1/20 0.39
CASP3 P42574 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PIK3CB P42338 2/20 0.39
PIK3CD O00329 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4465794 0.80 CYP1A2 (0.54) CYP1A2KMT2AMEN1MAPTALDH1A1
SCHEMBL30218146 0.80 CYP1A2 (0.49) CYP1A2KMT2AMEN1MAPTALDH1A1
SCHEMBL17759257 0.78 CYP1A2 (0.46) CYP1A2KMT2AMEN1MAPTALDH1A1
SCHEMBL17697709 0.75 CYP1A2 (0.44) CYP1A2KMT2AMEN1MAPTALDH1A1
SCHEMBL18766625 0.70 CYP1A2 (0.67) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL3020269 0.69 POLB (0.51) KMT2AMEN1MAPTALDH1A1LMNA
SCHEMBL30217954 0.69 MAP3K14 (0.40) CYP1A2ALDH1A1CYP2C9POLBPIK3CA
SCHEMBL16691133 0.69 TGFBR1 (0.50) CYP1A2MAPTCYP2C9GAANPC1
SCHEMBL16687033 0.68 MAPT (0.43) CYP1A2KMT2AMAPTALDH1A1CYP2C9
Bromide SCHEMBL3016136 0.68 POLB (0.50) KMT2AMEN1MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695246-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
CN-119707925-A Compounds as KIF18A inhibitors and uses thereof 南京圣和药物研发有限公司 2025-03-28 CN disclosed
WO-2024213653-A1 IMIDAZO[1,2-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed