Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143027 | 0.83 | CYP1A2 (0.67) | KMT2ACYP1A2HTTPDE4APDE4B | |
| SCHEMBL30047239 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL23857269 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL10983820 | 0.77 | CYP1A2 (0.61) | CYP1A2KDM4ECA1CA2POLB | |
| SCHEMBL30334623 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL9370934 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1L3MBTL1CYP1A2 | |
| SCHEMBL6075563 | 0.76 | KDM4E (0.55) | ALDH1A1KMT2ACYP1A2KDM4EHPGD | |
| SCHEMBL31143068 | 0.76 | PDE4A (0.40) | ALDH1A1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL10622306 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1ATML3MBTL1 | |
| SCHEMBL3949856 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4660185-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING AMIDES, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024159288-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING AMIDES, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2024-08-08 | — | — | WO | disclosed |