Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.74 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.53 |
| ▸ | KDM5A | P29375 | 8/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.51 |
| ▸ | KDM4A | O75164 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516867 | 1.00 | PIK3CA (0.74) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| Hydrochloric Acid SCHEMBL1252523 | 0.98 | PIK3CA (0.72) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| SCHEMBL30505327 | 0.98 | PIK3CA (0.72) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| SCHEMBL1255519 | 0.98 | PIK3CA (0.72) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| SCHEMBL27991055 | 0.88 | PIK3CA (0.58) | PIK3CAPROKR1CTSAPRKD3PRKD1 | |
| SCHEMBL20951723 | 0.87 | PIK3CA (0.62) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| SCHEMBL12552657 | 0.85 | PIK3CA (0.60) | PIK3CAKDM4CKDM5AKDM5BPROKR1 | |
| SCHEMBL1255470 | 0.85 | PIK3CA (1.00) | PIK3CAKDM4CKDM5AKDM5BKDM4E | |
| SCHEMBL28466905 | 0.85 | PIK3CA (0.68) | PIK3CAKDM4CKDM5AKDM5BKDM4E | |
| SCHEMBL20951481 | 0.85 | PIK3CA (0.68) | PIK3CAKDM4CKDM5AKDM5BKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974036-A | Inhibitors of RAF kinase | 皮埃尔法布雷医药公司 | 2024-11-15 | — | — | CN | disclosed |