Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | METAP2 | P50579 | 6/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16830014 | 1.00 | IDO1 (0.44) | IDO1METAP2NOS1DYRK1ATDO2 | |
| SCHEMBL9434885 | 0.80 | IDO1 (0.47) | IDO1METAP2NOS1TDO2DRD1 | |
| SCHEMBL30852842 | 0.80 | NOS1 (0.42) | IDO1METAP2NOS1DYRK1ATDO2 | |
| SCHEMBL16522812 | 0.80 | NOS1 (0.42) | IDO1METAP2NOS1DYRK1ATDO2 | |
| SCHEMBL9434922 | 0.74 | IDO1 (0.42) | IDO1METAP2TDO2FGFR1 | |
| SCHEMBL22693055 | 0.74 | IDO1 (0.42) | IDO1METAP2TDO2CHEK1CYP1A2 | |
| SCHEMBL2630775 | 0.73 | IDO1 (0.44) | IDO1METAP2NOS1DYRK1ATDO2 | |
| SCHEMBL8807904 | 0.73 | IDO1 (0.41) | IDO1METAP2TDO2DRD1CYP1A2 | |
| SCHEMBL20748554 | 0.73 | GSK3B (0.36) | IDO1METAP2TDO2PLK4PAK4 | |
| SCHEMBL8806195 | 0.72 | SMN1; SMN2 (0.41) | IDO1METAP2NOS1DYRK1ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024181803-A1 | HETEROARYL DERIVATIVE AND USE THEREOF | 보로노이 주식회사 | 2024-09-06 | — | — | WO | disclosed |