Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274780 | 0.83 | KMT2A (0.44) | KMT2ALMNAUSP2MAPK1SMN1; SMN2 | |
| SCHEMBL6470073 | 0.83 | HPGD (0.35) | KMT2AMAPK1SMN1; SMN2F2MAPT | |
| SCHEMBL9296714 | 0.82 | LMNA (0.48) | KMT2ALMNAUSP2POLBMAPK1 | |
| SCHEMBL31144941 | 0.79 | GLP1R (0.41) | KMT2ALMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL31144879 | 0.76 | MAPK1 (0.45) | KMT2ALMNAUSP2POLBMAPK1 | |
| SCHEMBL9296297 | 0.74 | LMNA (0.41) | KMT2ALMNAUSP2POLBMAPK1 | |
| SCHEMBL9277231 | 0.72 | KMT2A (0.39) | KMT2ALMNAMAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL10004533 | 0.71 | MAPT (0.40) | KMT2ALMNAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL537829 | 0.69 | MAPT (0.48) | KMT2ALMNAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL6095048 | 0.69 | HPGD (0.41) | KMT2ALMNAPOLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175804-A1 | NUCLEAR TRANSPORT MODULATORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-08-29 | — | — | WO | disclosed |