Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118844 | 0.94 | PTGS2 (0.52) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL13114177 | 0.91 | PTGS2 (0.46) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL3106411 | 0.84 | TDP1 (0.52) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL3106407 | 0.84 | TDP1 (0.52) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL12742987 | 0.83 | TDP1 (0.68) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL29893907 | 0.83 | TDP1 (0.68) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL13579048 | 0.83 | TDP1 (0.68) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL3113710 | 0.80 | PTGS2 (0.47) | PTGS2PTGS1AKR1C3AKR1C2TSHR | |
| SCHEMBL13109330 | 0.79 | PTGS2 (0.62) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 | |
| SCHEMBL3119087 | 0.79 | PTGS2 (0.62) | PTGS2TDP1L3MBTL1PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255050-A1 | Polyethylene Based Bioactive Agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2010-10-07 | — | — | US | disclosed |
| WO-2009015274-A2 | POLYETHYLENE BASED BIOACTIVE AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-01-29 | — | — | WO | disclosed |